Casey Ruble was raised on a ranch in eastern Montana. After receiving her BA from Smith College in 1995, she lived in New Orleans and Chicago, moving to New York in 1998 and completing her MFA at Hunter College in 2002. She has taught painting and drawing at Fordham University since 2001 and has worked as a freelance critic for Art in America since 2006, supplementing it with freelance copyediting for W. W. Norton’s Professional Books division (psychology books). 

Ruble is represented by Foley Gallery in New York City. Recent solo shows include Everything That Rises (at the Visual Arts Center of New Jersey, Summit), Disarmed (at Foley Gallery, New York), and The Offing (at the Foundation Gallery, New Orleans). Her work is included in the 2013 Unfathomable City: A New Orleans Atlas, edited by Rebecca Solnit and Rebecca Snedeker. A recipient of a 2015 grant from the New Jersey Council for the Humanities and a 2013 fellowship from the New Jersey Council on the Arts, Ruble currently resides in a village overlooking the Delaware River in New Jersey.